National Academy of Sciences
Proceedings of the National Academy of Sciences, Volume 122, Issue 6, February 2025.
SignificancePolyketides and lipids are important in biology and medicine. Almost all of the structural and biochemical work on polyketide biosynthetic machinery describes microbial systems. Animals nearly always have their own unique sets of polyketide …
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The structure of full-length AFPK supports the ACP linker in a role that regulates iterative polyketide and fatty acid assembly
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Proceedings of the National Academy of Sciences, Volume 122, Issue 6, February 2025. SignificancePolyketides and lipids are important in biology and medicine. Almost all of the structural and biochemical work on polyketide biosynthetic machinery describes microbial systems. Animals nearly always have their own unique sets of polyketide …
