National Academy of Sciences
Proceedings of the National Academy of Sciences, Volume 122, Issue 26, July 2025.
SignificanceChronic pain is a major global health issue with few effective long-term treatments. While abnormal signaling in the anterior cingulate cortex (ACC) is known to drive chronic pain, the underlying mechanisms remain unclear…
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Synergistic deficits in parvalbumin interneurons and dopamine signaling drive ACC dysfunction in chronic pain
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Proceedings of the National Academy of Sciences, Volume 122, Issue 26, July 2025. SignificanceChronic pain is a major global health issue with few effective long-term treatments. While abnormal signaling in the anterior cingulate cortex (ACC) is known to drive chronic pain, the underlying mechanisms remain unclear…
