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Polyglycine-mediated aggregation of FAM98B disrupts tRNA processing in GGC repeat disorders | Science

Home » Science & Technology » Polyglycine-mediated aggregation of FAM98B disrupts tRNA processing in GGC repeat disorders | Science

Polyglycine-mediated aggregation of FAM98B disrupts tRNA processing in GGC repeat disorders | Science

Raleigh Antes 21/07/2025 08:20

Aggregation-prone polyglycine-containing proteins produced from expanded GGC repeats are implicated in an emerging family of neurodegenerative disorders. In this study, we showed that polyglycine itself forms aggregates that incorporate endogenous …

ScienceMag
Aggregation-prone polyglycine-containing proteins produced from expanded GGC repeats are implicated in an emerging family of neurodegenerative disorders. In this study, we showed that polyglycine itself forms aggregates that incorporate endogenous …
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