Nature.com
Nature Biotechnology, Published online: 18 August 2025; doi:10.1038/s41587-025-02781-yPepMLM, a protein language model fine-tuned on protein–peptide data, can generate potent, target-specific linear peptides capable of binding to and degrading proteins ranging from cancer receptors to drivers of neurodegeneration and viral proteins, all without requiring protein structural information…
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Peptide binders designed directly from protein sequences
Nature Biotechnology, Published online: 18 August 2025; doi:10.1038/s41587-025-02781-yPepMLM, a protein language model fine-tuned on protein–peptide data, can generate potent, target-specific linear peptides capable of binding to and degrading proteins ranging from cancer receptors to drivers of neurodegeneration and viral proteins, all without requiring protein structural information…