National Academy of Sciences
Proceedings of the National Academy of Sciences, Volume 122, Issue 32, August 2025.
SignificanceThe successful export of messenger RNA (mRNA) from the cell’s nucleus is a key step in turning genes into proteins. This study shows that a specific chemical “tag” on proteins—called O-GlcNAc—plays a major role in regulating how mRNA passes …
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O-GlcNAc modulation of nuclear pore complexes orchestrates mRNA export efficiency
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Proceedings of the National Academy of Sciences, Volume 122, Issue 32, August 2025. SignificanceThe successful export of messenger RNA (mRNA) from the cell’s nucleus is a key step in turning genes into proteins. This study shows that a specific chemical “tag” on proteins—called O-GlcNAc—plays a major role in regulating how mRNA passes …
