National Academy of Sciences
Proceedings of the National Academy of Sciences, Volume 122, Issue 13, April 2025.
SignificanceDengue virus (DENV) is the most important mosquito-borne flavivirus affecting humans, yet no effective therapies exist. NITD-688 represents a promising panserotype DENV drug candidate currently in Phase II clinical trials. Understanding the …
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Mechanistic insights into dengue virus inhibition by a clinical trial compound NITD-688
Proceedings of the National Academy of Sciences, Volume 122, Issue 13, April 2025. SignificanceDengue virus (DENV) is the most important mosquito-borne flavivirus affecting humans, yet no effective therapies exist. NITD-688 represents a promising panserotype DENV drug candidate currently in Phase II clinical trials. Understanding the …