National Academy of Sciences
Proceedings of the National Academy of Sciences, Volume 122, Issue 17, April 2025.
SignificanceOnly a few dozen RNA–ligand complexes, involving small molecules with favorable (drug-like) physicochemical properties, have been visualized at high resolution. Manipulation of RNA biology using small molecule ligands is thus a promising, yet …
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Ligand-binding pockets in RNA and where to find them
Proceedings of the National Academy of Sciences, Volume 122, Issue 17, April 2025. SignificanceOnly a few dozen RNA–ligand complexes, involving small molecules with favorable (drug-like) physicochemical properties, have been visualized at high resolution. Manipulation of RNA biology using small molecule ligands is thus a promising, yet …