Phys.org
The serine 31 (Ser31) phosphorylation modification (H3.3S31ph) in the N-terminal tail of the histone variant H3.3 can transform H3.3 nucleosomes from a stable state to a dynamically activated configuration, providing new insights into the mechanisms of epigenetic regulation. However, the specific mechanisms by which H3.3 influences nucleosome stability and dynamics remain unclear…
Read More
How a histone ‘switch’ regulates chromatin dynamics
Sharie Stoval
16:20
The serine 31 (Ser31) phosphorylation modification (H3.3S31ph) in the N-terminal tail of the histone variant H3.3 can transform H3.3 nucleosomes from a stable state to a dynamically activated configuration, providing new insights into the mechanisms of epigenetic regulation. However, the specific mechanisms by which H3.3 influences nucleosome stability and dynamics remain unclear…
