National Academy of Sciences
Proceedings of the National Academy of Sciences, Volume 122, Issue 6, February 2025.
SignificanceMycobacterial infections are among the leading causes of human deaths globally. Ribosome-targeting antibiotics are often included among their treatment regimens. HflX is a bacterial stress-response protein that binds to the 70S ribosomes and …
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HflX-mediated drug resistance through ribosome splitting and rRNA disordering in mycobacteria
Proceedings of the National Academy of Sciences, Volume 122, Issue 6, February 2025. SignificanceMycobacterial infections are among the leading causes of human deaths globally. Ribosome-targeting antibiotics are often included among their treatment regimens. HflX is a bacterial stress-response protein that binds to the 70S ribosomes and …