National Academy of Sciences
Proceedings of the National Academy of Sciences, Volume 122, Issue 21, May 2025.
SignificanceThe cytosolic innate immune sensor NLRP12 induces inflammatory cell death, PANoptosis, in response to homeostatic disruptions and infection. NLRP12-mediated PANoptosis has been implicated in hemolytic and inflammatory diseases, but the …
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HCK regulates NLRP12-mediated PANoptosis
Proceedings of the National Academy of Sciences, Volume 122, Issue 21, May 2025. SignificanceThe cytosolic innate immune sensor NLRP12 induces inflammatory cell death, PANoptosis, in response to homeostatic disruptions and infection. NLRP12-mediated PANoptosis has been implicated in hemolytic and inflammatory diseases, but the …