National Academy of Sciences
Proceedings of the National Academy of Sciences, Volume 122, Issue 26, July 2025.
SignificanceMetabolic reprogramming is a notable phenotype during the acquisition of resistance to chemotherapy drugs. Thus, reverting metabolism can be an effective strategy to sensitize drug-resistant cells. The computational framework developed in this …
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Genome-scale knockout simulation and clustering analysis of drug-resistant breast cancer cells reveal drug sensitization targets
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Proceedings of the National Academy of Sciences, Volume 122, Issue 26, July 2025. SignificanceMetabolic reprogramming is a notable phenotype during the acquisition of resistance to chemotherapy drugs. Thus, reverting metabolism can be an effective strategy to sensitize drug-resistant cells. The computational framework developed in this …
