National Academy of Sciences
Proceedings of the National Academy of Sciences, Volume 122, Issue 26, July 2025.
SignificanceThe steroidogenic enzyme 3β-hydroxysteroid dehydrogenase type 1 (3βHSD1) correlates with tumor aggressiveness, and its inhibitors, biochanin-A (BCA) and the related analogs, have shown antitumor activities in various preclinical models and …
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Fine structural design of 3βHSD1 inhibitors for prostate cancer therapy
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Proceedings of the National Academy of Sciences, Volume 122, Issue 26, July 2025. SignificanceThe steroidogenic enzyme 3β-hydroxysteroid dehydrogenase type 1 (3βHSD1) correlates with tumor aggressiveness, and its inhibitors, biochanin-A (BCA) and the related analogs, have shown antitumor activities in various preclinical models and …
