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Nature Biotechnology, Published online: 11 September 2024; doi:10.1038/s41587-024-02345-6Satellite cells, the stem cells of skeletal muscle, are responsible for muscle development and regeneration. Although low in abundance, satellite cells can be isolated from muscle but cannot be propagated successfully in culture in numbers needed for therapeutic use…
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Dedifferentiating myoblasts back into a satellite cell state in vitro
Nature Biotechnology, Published online: 11 September 2024; doi:10.1038/s41587-024-02345-6Satellite cells, the stem cells of skeletal muscle, are responsible for muscle development and regeneration. Although low in abundance, satellite cells can be isolated from muscle but cannot be propagated successfully in culture in numbers needed for therapeutic use…