National Academy of Sciences
Proceedings of the National Academy of Sciences, Volume 122, Issue 26, July 2025.
SignificanceAlthough D-peptides offer superior metabolic stability and immunogenicity properties compared to L-peptides, their discovery has been limited by current screening methods. We introduce a computational strategy for the de novo design of D…
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De novo design of D-peptide ligands: Application to influenza virus hemagglutinin
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Proceedings of the National Academy of Sciences, Volume 122, Issue 26, July 2025. SignificanceAlthough D-peptides offer superior metabolic stability and immunogenicity properties compared to L-peptides, their discovery has been limited by current screening methods. We introduce a computational strategy for the de novo design of D…
