National Academy of Sciences
Proceedings of the National Academy of Sciences, Volume 122, Issue 16, April 2025.
SignificancePseudohypoparathyroidism type 1B (PHP1B) is a disorder caused by end-organ hormone resistance due to epigenetic alterations atGNAS,a complex locus encoding Gsα as well as other sense and antisense RNAs. The promoters of these transcripts are …
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Bidirectional disruption of GNAS transcripts causes broad methylation defects in pseudohypoparathyroidism type 1B
Proceedings of the National Academy of Sciences, Volume 122, Issue 16, April 2025. SignificancePseudohypoparathyroidism type 1B (PHP1B) is a disorder caused by end-organ hormone resistance due to epigenetic alterations atGNAS,a complex locus encoding Gsα as well as other sense and antisense RNAs. The promoters of these transcripts are …