National Academy of Sciences
Proceedings of the National Academy of Sciences, Volume 122, Issue 17, April 2025.
SignificanceChronic inflammatory skin disorders affect millions worldwide. Our study reveals a role for acetylcholine (ACh), a molecule typically associated with neuronal signaling, in regulating skin health. We demonstrate that B cells produce ACh to …
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B cell–derived acetylcholine mitigates skin inflammation in mice through α9 nicotinic acetylcholine receptor–mediated signaling
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Proceedings of the National Academy of Sciences, Volume 122, Issue 17, April 2025. SignificanceChronic inflammatory skin disorders affect millions worldwide. Our study reveals a role for acetylcholine (ACh), a molecule typically associated with neuronal signaling, in regulating skin health. We demonstrate that B cells produce ACh to …
