National Academy of Sciences
Proceedings of the National Academy of Sciences, Volume 122, Issue 34, August 2025.
SignificanceThe stability of the folded back blocked head configuration (BHC) of the interacting-heads motif (IHM) state of β-cardiac myosin is linked to the pathological effects of myosin cardiomyopathy mutations. Myosin sequestration is often measured …
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A FRET assay to monitor different structural states of human β-cardiac myosin including the interacting-heads motif
Proceedings of the National Academy of Sciences, Volume 122, Issue 34, August 2025. SignificanceThe stability of the folded back blocked head configuration (BHC) of the interacting-heads motif (IHM) state of β-cardiac myosin is linked to the pathological effects of myosin cardiomyopathy mutations. Myosin sequestration is often measured …