National Academy of Sciences
Proceedings of the National Academy of Sciences, Volume 122, Issue 17, April 2025.
SignificanceThis study reveals a previously uncharacterized mechanism regulating UDP-GlcUA levels inCryptococcus gattii,an etiologic agent of cryptococcosis. Our findings indicate thatUXS1deletion leads to the accumulation of UDP-GlcUA, which enhances …
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Elevated UDP-glucuronic acid levels mend drug resistance and stress responses via a protease and a transporter in Cryptococcus gattii
Proceedings of the National Academy of Sciences, Volume 122, Issue 17, April 2025. SignificanceThis study reveals a previously uncharacterized mechanism regulating UDP-GlcUA levels inCryptococcus gattii,an etiologic agent of cryptococcosis. Our findings indicate thatUXS1deletion leads to the accumulation of UDP-GlcUA, which enhances …