National Academy of Sciences
Proceedings of the National Academy of Sciences, Volume 122, Issue 15, April 2025.
SignificanceThe adaptation of an organism to environmental stress often involves a loss of fitness in the stress-free environment. Upon removal of the stress, this loss can be mitigated by compensatory evolution through mutations that are not involved in …
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Epistasis-mediated compensatory evolution in a fitness landscape with adaptational tradeoffs
Proceedings of the National Academy of Sciences, Volume 122, Issue 15, April 2025. SignificanceThe adaptation of an organism to environmental stress often involves a loss of fitness in the stress-free environment. Upon removal of the stress, this loss can be mitigated by compensatory evolution through mutations that are not involved in …