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Nature Biotechnology, Published online: 28 March 2025; doi:10.1038/s41587-025-02639-3Gene transfer enables bacteria to adapt to their environment. To sensitively detect gene transfer, we created a synthetic biology tool that introduces an identifiable barcode into RNA when microbes exchange DNA. When applied in a wastewater community, high-throughput sequencing revealed which microbes in the community participated in gene transfer…
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Sensitive detection of gene transfer in a microbial community
Becki Kazmierczak
04:20
Nature Biotechnology, Published online: 28 March 2025; doi:10.1038/s41587-025-02639-3Gene transfer enables bacteria to adapt to their environment. To sensitively detect gene transfer, we created a synthetic biology tool that introduces an identifiable barcode into RNA when microbes exchange DNA. When applied in a wastewater community, high-throughput sequencing revealed which microbes in the community participated in gene
