Nature.com
Nature Biotechnology, Published online: 27 March 2025; doi:10.1038/s41587-025-02640-wWe introduce volumetric DNA microscopy, a technique that enables three-dimensional imaging of tissue morphology and gene expression in a single measurement. This feat is achieved by forming a huge intermolecular network of DNA barcodes within an intact specimen and encoding their pairwise proximities into a DNA sequence library…
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Volumetric imaging using a distributed molecular network
Diego Kazmierczak
17:20
Nature Biotechnology, Published online: 27 March 2025; doi:10.1038/s41587-025-02640-wWe introduce volumetric DNA microscopy, a technique that enables three-dimensional imaging of tissue morphology and gene expression in a single measurement. This feat is achieved by forming a huge intermolecular network of DNA barcodes within an intact specimen and encoding their pairwise proximities into a DNA sequence library…
